Statements (43)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
microRNA gene
|
| gptkbp:alias |
gptkb:miR-34a
hsa-mir-34a microRNA 34a |
| gptkbp:associatedWith |
gptkb:cancer
neurodegenerative diseases tumor suppression |
| gptkbp:downregulatedIn |
multiple cancers
|
| gptkbp:encodes |
microRNA-34a
|
| gptkbp:Entrez_Gene_ID |
407040
ENSG00000207901 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:HGNC_ID |
31588
|
| https://www.w3.org/2000/01/rdf-schema#label |
MIR34A gene
|
| gptkbp:involvedIn |
DNA damage response
cell cycle arrest p53 signaling pathway apoptosis pathway cellular senescence pathway |
| gptkbp:locatedOnChromosome |
gptkb:1p36.22
chromosome 1 |
| gptkbp:miRBase_ID |
MI0000268
|
| gptkbp:OMIM |
611036
|
| gptkbp:orthologInMouse |
Mir34a
|
| gptkbp:regulates |
apoptosis
cell differentiation cell proliferation cell cycle senescence epithelial-mesenchymal transition |
| gptkbp:target |
gptkb:SIRT1
gptkb:E2F3 gptkb:AXL gptkb:MET gptkb:CDK6 gptkb:BCL2 gptkb:CCND1 gptkb:MYC gptkb:NOTCH1 PD-L1 |
| gptkbp:transcriptionallyActivatedBy |
gptkb:TP53
|
| gptkbp:bfsParent |
gptkb:miR-34a
|
| gptkbp:bfsLayer |
7
|