Statements (75)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DNA
|
| gptkbp:associated_with |
cell differentiation
cell proliferation neurogenesis |
| gptkbp:conservation |
many species
|
| gptkbp:genetic_studies |
gptkb:Oncology
gptkb:T-cell_acute_lymphoblastic_leukemia |
| gptkbp:has_role |
gptkb:embryonic_development
|
| gptkbp:has_variants |
multiple isoforms
|
| https://www.w3.org/2000/01/rdf-schema#label |
NOTCH1
|
| gptkbp:initiated_by |
apoptosis
transcription factors |
| gptkbp:interacts_with |
other Notch receptors
|
| gptkbp:involved_in |
Notch signaling pathway
|
| gptkbp:is_associated_with |
gptkb:neurodegenerative_diseases
differentiation of stem cells |
| gptkbp:is_essential_for |
cell fate determination
|
| gptkbp:is_expressed_in |
gptkb:hematopoietic_stem_cells
various tissues endothelial cells |
| gptkbp:is_involved_in |
gptkb:oogenesis
gptkb:spermatogenesis immune response muscle development chondrogenesis eye development neural development placental development erythropoiesis thymocyte development tooth development vascular development hair follicle development osteogenesis kidney development hematopoiesis lung development neural crest development adipogenesis neural tube closure cardiac development T-cell development pancreatic development skin development mast cell development cell-cell communication liver development intestinal development B-cell development ear development NK cell development basophil development dendritic cell development embryonic stem cell maintenance eosinophil development gland development lymphoid development lymphopoiesis macrophage development monocyte development myeloid development myelopoiesis neutrophil development platelet development thrombopoiesis |
| gptkbp:is_linked_to |
cancer progression
metastasis |
| gptkbp:is_part_of |
cell signaling pathways
|
| gptkbp:is_regulated_by |
ligands
|
| gptkbp:is_studied_in |
cancer research
|
| gptkbp:is_targeted_at |
therapeutic agents
|
| gptkbp:located_in |
human chromosome 9
|
| gptkbp:regulates |
gene expression
|
| gptkbp:bfsParent |
gptkb:Oncology
|
| gptkbp:bfsLayer |
4
|