|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:HLA_complex_(human)
gptkb:H-2_complex_(mouse)
|
|
gptkbp:component
|
gptkb:adaptive_immune_system
|
|
gptkbp:discoveredBy
|
gptkb:Jean_Dausset
|
|
gptkbp:encodes
|
gptkb:MHC_proteins
|
|
gptkbp:expressedIn
|
all nucleated cells (class I)
antigen-presenting cells (class II)
|
|
gptkbp:foundIn
|
vertebrates
|
|
gptkbp:fullName
|
gptkb:Major_Histocompatibility_Complex
|
|
gptkbp:function
|
antigen presentation
|
|
gptkbp:hasPolymorphism
|
yes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MHC complex
|
|
gptkbp:involvedIn
|
graft rejection
pathogen recognition
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6_(human)
|
|
gptkbp:location
|
cell surface
|
|
gptkbp:presentedPeptides
|
13-18 amino acids (class II)
8-10 amino acids (class I)
|
|
gptkbp:recognizedBy
|
gptkb:T_cells
|
|
gptkbp:relatedTo
|
organ transplantation
autoimmune diseases
histocompatibility
|
|
gptkbp:requires
|
self/non-self discrimination
|
|
gptkbp:role
|
immune response
|
|
gptkbp:species
|
yes
|
|
gptkbp:type
|
gptkb:MHC_class_II
gptkb:MHC_class_I
gptkb:MHC_class_III
|
|
gptkbp:bfsParent
|
gptkb:major_histocompatibility_complex_(MHC)
|
|
gptkbp:bfsLayer
|
6
|