Major Histocompatibility Complex

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:abbreviation	gptkb:MHC
gptkbp:component	gptkb:adaptive_immune_system
gptkbp:discoveredBy	gptkb:Jean_Dausset
gptkbp:discoveredIn	1958
gptkbp:encodes	cell surface proteins
gptkbp:expressedIn	gptkb:cell_membrane
gptkbp:foundIn	vertebrates
gptkbp:function	antigen presentation immune response regulation
gptkbp:hasPolymorphism	yes
https://www.w3.org/2000/01/rdf-schema#label	Major Histocompatibility Complex
gptkbp:importantFor	organ transplantation vaccine response disease susceptibility
gptkbp:involvedIn	gptkb:graft-versus-host_disease T cell activation pathogen recognition
gptkbp:locatedOnChromosome	gptkb:chromosome_6_(human)
gptkbp:mayInclude	gptkb:MHC_class_II gptkb:MHC_class_I gptkb:MHC_class_III
gptkbp:orthologIn	gptkb:cattle_(BoLA_complex) gptkb:chicken_(B_complex) gptkb:dog_(DLA_complex) gptkb:mouse_(H-2_complex)
gptkbp:relatedTo	gptkb:human_leukocyte_antigen autoimmune diseases transplant rejection
gptkbp:species	yes
gptkbp:studiedIn	immunogenetics
gptkbp:bfsParent	gptkb:Chromosome_6 gptkb:MHC_complex gptkb:MHC
gptkbp:bfsLayer	7