major histocompatibility complex (MHC)
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:HLA_complex_(human)
gptkb:MHC_complex |
| gptkbp:associatedWith |
autoimmune diseases
organ transplant compatibility |
| gptkbp:component |
gptkb:adaptive_immune_system
|
| gptkbp:discoveredBy |
gptkb:Jean_Dausset
|
| gptkbp:encodes |
gptkb:MHC_class_III_molecules
gptkb:MHC_class_II_molecules gptkb:MHC_class_I_molecules |
| gptkbp:foundIn |
vertebrates
|
| gptkbp:function |
antigen presentation
immune response regulation |
| gptkbp:hasPolymorphism |
true
|
| gptkbp:locatedOn |
gptkb:chromosome_6_(human)
|
| gptkbp:presentIn |
all jawed vertebrates
|
| gptkbp:proteinFamily |
gptkb:immunoglobulin_superfamily
|
| gptkbp:role |
T cell activation
self/non-self recognition |
| gptkbp:studiedIn |
immunology
|
| gptkbp:bfsParent |
gptkb:George_Snell
|
| gptkbp:bfsLayer |
5
|
| https://www.w3.org/2000/01/rdf-schema#label |
major histocompatibility complex (MHC)
|