Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
major histocompatibility complex molecule |
| gptkbp:alternativeName |
gptkb:MHC_class_II
major histocompatibility complex class II |
| gptkbp:associatedWith |
autoimmune diseases
|
| gptkbp:encodedBy |
gptkb:MHC_class_II_genes
|
| gptkbp:expressedIn |
gptkb:B_cells
dendritic cells macrophages antigen-presenting cells |
| gptkbp:foundIn |
vertebrates
|
| gptkbp:function |
presentation of extracellular antigens
|
| https://www.w3.org/2000/01/rdf-schema#label |
class II MHC
|
| gptkbp:importantFor |
adaptive immune response
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_6_(human)
|
| gptkbp:peptideBindingGroove |
open at both ends
|
| gptkbp:peptideLength |
13-25 amino acids
|
| gptkbp:recognizedBy |
gptkb:CD4+_T_cells
|
| gptkbp:species |
gptkb:human
gptkb:mouse |
| gptkbp:structure |
heterodimer
|
| gptkbp:subunit |
alpha chain
beta chain |
| gptkbp:type |
gptkb:HLA-DP
gptkb:HLA-DQ gptkb:HLA-DR |
| gptkbp:bfsParent |
gptkb:MHC_class_II
|
| gptkbp:bfsLayer |
7
|