MEF2 transcription factors

URI: https://gptkb.org/entity/MEF2_transcription_factors
GPTKB entity
Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:protein
transcription factor
gptkbp:activatedBy calcium signaling
MAPK signaling
gptkbp:associatedWith gptkb:cancer
gptkb:synaptic_plasticity
apoptosis
neurogenesis
cardiomyopathy
muscular dystrophy
myogenesis
cardiogenesis
gptkbp:binds gptkb:gene
MEF2 consensus sequence
gptkbp:contains gptkb:MEF2C
gptkb:MEF2A
gptkb:MEF2D
MEF2B
gptkbp:discoveredIn 1992
gptkbp:domain gptkb:MEF2_domain
MADS domain
gptkbp:encodedBy MEF2C gene
MEF2A gene
MEF2B gene
MEF2D gene
gptkbp:expressedIn gptkb:skeletal_muscle
brain
cardiac muscle
https://www.w3.org/2000/01/rdf-schema#label MEF2 transcription factors
gptkbp:inhibitedBy class II HDACs
gptkbp:interactsWith gptkb:14-3-3_proteins
gptkb:MAPK
HDACs
gptkbp:locatedIn gptkb:nucleus
gptkbp:memberOf MADS-box protein family
gptkbp:modulatedBy phosphorylation
sumoylation
acetylation
gptkbp:orthologIn gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkb:Caenorhabditis_elegans
gptkb:Drosophila_melanogaster
gptkbp:regulates gene expression
neuronal differentiation
muscle development
cardiac development
muscle-specific genes
cardiac-specific genes
neuronal activity-dependent genes
gptkbp:bfsParent gptkb:ERK5_pathway
gptkbp:bfsLayer 7