|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Mitogen-activated_protein_kinase-associated_protein_1
gptkb:mSin1
|
|
gptkbp:associatedComplex
|
gptkb:mTORC2
|
|
gptkbp:discoveredIn
|
2002
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000137073
9446
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:function
|
component of mTORC2 complex
involved in cell growth and survival
regulates Akt/PKB signaling
|
|
gptkbp:gene
|
gptkb:MAPKAP1
|
|
gptkbp:geneType
|
protein-coding
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPKAP1
|
|
gptkbp:interactsWith
|
gptkb:RICTOR
gptkb:mTOR
gptkb:SIN1
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_9
9q22.31
|
|
gptkbp:molecularWeight
|
approximately 58 kDa
|
|
gptkbp:OMIM
|
609192
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Mapkap1
|
|
gptkbp:pathway
|
gptkb:mTOR_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
|
|
gptkbp:phosphorylates
|
gptkb:Akt
|
|
gptkbp:RefSeq
|
NM_014417
|
|
gptkbp:regulates
|
cell proliferation
cell survival
metabolism
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:Q9BPZ7
|
|
gptkbp:bfsParent
|
gptkb:mTORC2
|
|
gptkbp:bfsLayer
|
6
|