Dual leucine zipper-bearing kinase
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:MAP3K12
gptkb:DLK |
| gptkbp:discoveredBy |
1996
|
| gptkbp:enzymeCommissionNumber |
2.7.11.25
|
| gptkbp:expressedIn |
brain
neurons |
| gptkbp:function |
gptkb:MAP_kinase_kinase_kinase
serine/threonine protein kinase |
| gptkbp:gene |
gptkb:MAP3K12
gptkb:DLK |
| https://www.w3.org/2000/01/rdf-schema#label |
Dual leucine zipper-bearing kinase
|
| gptkbp:interactsWith |
gptkb:MKK7
JIP proteins |
| gptkbp:involves |
apoptosis
neuronal development axon regeneration |
| gptkbp:locatedOnChromosome |
12q13.12
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
~100 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Map3k12
|
| gptkbp:phosphorylates |
gptkb:MAP2K7
JNK pathway proteins |
| gptkbp:regulates |
neurite outgrowth
neuronal apoptosis |
| gptkbp:structure |
kinase domain
dual leucine zipper domain |
| gptkbp:UniProtID |
Q12852
|
| gptkbp:bfsParent |
gptkb:MAP3K12
gptkb:Map3k12 |
| gptkbp:bfsLayer |
8
|