Statements (93)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biomedical research program
|
| gptkbp:application |
precision medicine
drug discovery systems biology disease mechanism elucidation |
| gptkbp:availableOn |
gptkb:LINCS_Data_Portal
|
| gptkbp:collaboratesWith |
gptkb:Broad_Institute
gptkb:Columbia_University gptkb:Harvard_Medical_School gptkb:University_of_Miami gptkb:Mount_Sinai_School_of_Medicine |
| gptkbp:dataCollected |
proteomics
gene expression cellular phenotypes |
| gptkbp:focusesOn |
cellular response to perturbations
|
| gptkbp:fullName |
gptkb:Library_of_Integrated_Network-based_Cellular_Signatures
|
| gptkbp:fundedBy |
gptkb:NIH
|
| gptkbp:goal |
to create a network-based understanding of cell biology
|
| gptkbp:hasAssay |
gptkb:confocal_microscopy
gptkb:siRNA gptkb:ELISA gptkb:shRNA gptkb:ATAC-seq gptkb:Hi-C gptkb:CRISPR gptkb:RNAi gptkb:L1000 gptkb:RPPA gptkb:cell_painting gptkb:qHTS gptkb:single-cell_RNA-seq metabolomics single-cell genomics electron microscopy immunoassays Mass spectrometry super-resolution microscopy Imaging western blot FACS ChIP-seq immunohistochemistry immunofluorescence mass cytometry apoptosis assays cell viability assays live-cell imaging DNA methylation profiling Flow cytometry cell cycle assays chemical perturbation differentiation assays enzyme activity assays fixed-cell imaging genetic perturbation high-content screening immunoprecipitation invasion assays luciferase assays migration assays multiplex assays phosphoproteomics proliferation assays proteomics mass spectrometry reporter assays single-cell epigenomics single-cell proteomics single-cell transcriptomics small molecule screening |
| gptkbp:hasResource |
gptkb:LINCS_Data_Portal
gptkb:L1000_assay gptkb:LINCS_Cloud gptkb:GEO_(Gene_Expression_Omnibus) gptkb:CLUE_(Connectivity_Map) gptkb:LINCS_Canvas_Browser gptkb:iLINCS |
| https://www.w3.org/2000/01/rdf-schema#label |
LINCS
|
| gptkbp:partOf |
gptkb:NIH_Common_Fund
|
| gptkbp:startYear |
2011
|
| gptkbp:technology |
bioinformatics
computational modeling high-throughput screening |
| gptkbp:type |
epigenomics
proteomics cellular imaging transcriptomics genetic perturbations perturbagen signatures small molecule responses |
| gptkbp:website |
https://lincsproject.org/
|
| gptkbp:bfsParent |
gptkb:Library_of_Integrated_Network-based_Cellular_Signatures
gptkb:NIH_LINCS_program |
| gptkbp:bfsLayer |
6
|