|
gptkbp:instanceOf
|
genomics technique
|
|
gptkbp:advantage
|
high resolution
fast protocol
low input requirement
|
|
gptkbp:analyzes
|
gptkb:ATACseqQC
gptkb:ArchR
gptkb:MACS2
gptkb:Signac
|
|
gptkbp:application
|
cancer research
developmental biology
disease research
single-cell analysis
|
|
gptkbp:database
|
gptkb:ArrayExpress
gptkb:ENCODE
gptkb:GEO
|
|
gptkbp:developedBy
|
gptkb:Howard_Y._Chang
gptkb:Jason_D._Buenrostro
gptkb:William_J._Greenleaf
|
|
gptkbp:fullName
|
gptkb:Assay_for_Transposase-Accessible_Chromatin_using_sequencing
|
|
gptkbp:hasBiologicalActivity
|
gptkb:Tn5_transposase
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ATAC-seq
|
|
gptkbp:limitation
|
mitochondrial DNA contamination
requires fresh samples
sequence bias
|
|
gptkbp:material
|
cells
nuclei
|
|
gptkbp:publicationYear
|
2013
|
|
gptkbp:publishedIn
|
gptkb:Nature_Methods
|
|
gptkbp:relatedTo
|
gptkb:FAIRE-seq
gptkb:MNase-seq
DNase-seq
|
|
gptkbp:sequencingPlatform
|
gptkb:Illumina
gptkb:HiSeq
gptkb:NextSeq
gptkb:NovaSeq
|
|
gptkbp:supportsProtocol
|
sequencing
PCR amplification
tagmentation
|
|
gptkbp:type
|
next-generation sequencing
|
|
gptkbp:usedFor
|
epigenomics
chromatin accessibility profiling
identifying open chromatin regions
mapping nucleosome positions
transcription factor binding site identification
|
|
gptkbp:variant
|
gptkb:multiome_ATAC-seq
gptkb:scATAC-seq
gptkb:single-cell_ATAC-seq
|
|
gptkbp:bfsParent
|
gptkb:ENCODE
|
|
gptkbp:bfsLayer
|
6
|