Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
RNA molecule
|
| gptkbp:discoveredIn |
early 2000s
|
| gptkbp:effect |
post-transcriptional gene silencing
|
| gptkbp:expressedIn |
gptkb:virus
plasmid vector |
| gptkbp:fullName |
short hairpin RNA
|
| https://www.w3.org/2000/01/rdf-schema#label |
shRNA
|
| gptkbp:introduced |
transfection
|
| gptkbp:mechanismOfAction |
gptkb:RNA_interference
|
| gptkbp:processor |
gptkb:Dicer_enzyme
|
| gptkbp:produces |
gptkb:siRNA
|
| gptkbp:relatedTo |
gptkb:miRNA
gptkb:siRNA |
| gptkbp:structure |
hairpin loop
|
| gptkbp:target |
gptkb:gene
|
| gptkbp:usedIn |
cancer research
gene silencing functional genomics therapeutic research gene knockdown drug target validation |
| gptkbp:bfsParent |
gptkb:siRNA
gptkb:LINCS |
| gptkbp:bfsLayer |
7
|