|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
CD85j
HM18
ILT2
LIR-1
MIR7
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
autoimmune diseases
|
|
gptkbp:binds
|
gptkb:MHC_class_I_molecules
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
1997
|
|
gptkbp:domain
|
immunoglobulin-like domain
ITIM (immunoreceptor tyrosine-based inhibitory motif)
|
|
gptkbp:Entrez_Gene_ID
|
10859
ENSG00000151012
|
|
gptkbp:expressedIn
|
gptkb:natural_killer_cells
gptkb:B_cells
gptkb:T_cells
dendritic cells
monocytes
|
|
gptkbp:fullName
|
leukocyte immunoglobulin like receptor subfamily B member 1
|
|
gptkbp:function
|
regulates immune response
inhibitory receptor on immune cells
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
gptkb:GO:0006955_(immune_response)
GO:0001772 (immunological synapse formation)
|
|
gptkbp:HGNC_ID
|
HGNC:6607
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
LILRB1
|
|
gptkbp:interactsWith
|
gptkb:HLA-A
gptkb:HLA-B
gptkb:HLA-C
gptkb:HLA-F
gptkb:HLA-G
|
|
gptkbp:length
|
650
|
|
gptkbp:locatedOnChromosome
|
19
|
|
gptkbp:location
|
19q13.4
|
|
gptkbp:modulatedBy
|
inflammatory response
immune tolerance
|
|
gptkbp:molecularWeight
|
~72 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Lilrb1
|
|
gptkbp:PDB
|
4LL9
|
|
gptkbp:product
|
Leukocyte immunoglobulin-like receptor subfamily B member 1 protein
|
|
gptkbp:regulates
|
phagocytosis
cytokine production
cell activation
|
|
gptkbp:subcellularLocation
|
cell surface
|
|
gptkbp:transmembraneDomains
|
true
|
|
gptkbp:UniProtID
|
Q8N423
|
|
gptkbp:bfsParent
|
gptkb:LILR
|
|
gptkbp:bfsLayer
|
7
|