|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:KSR
KSR-1
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000171105
8844
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
Kinase Suppressor of Ras 1
|
|
gptkbp:function
|
scaffold protein in MAPK/ERK signaling pathway
|
|
gptkbp:gene
|
gptkb:KSR1
|
|
gptkbp:HGNC_ID
|
HGNC:6467
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KSR1
|
|
gptkbp:interactsWith
|
gptkb:14-3-3_proteins
gptkb:ERK1/2
gptkb:MEK1
gptkb:BRAF
|
|
gptkbp:involvedIn
|
cell differentiation
cell proliferation
cell signaling
|
|
gptkbp:length
|
873 amino acids
|
|
gptkbp:locatedOnChromosome
|
17
|
|
gptkbp:location
|
gptkb:17q23.3
|
|
gptkbp:modulatedBy
|
signal transduction
|
|
gptkbp:molecularWeight
|
99 kDa
|
|
gptkbp:OMIM
|
603267
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:phosphorylates
|
regulates activity
|
|
gptkbp:regulates
|
gptkb:MAPK_pathway
gptkb:Raf/MEK/ERK_cascade
apoptosis
cell growth
|
|
gptkbp:relatedTo
|
Ras signaling
|
|
gptkbp:UniProtID
|
Q8IVT5
|
|
gptkbp:bfsParent
|
gptkb:RAF1_gene
gptkb:BRAF_(human)
|
|
gptkbp:bfsLayer
|
7
|