Interferon signaling pathway
GPTKB entity
Statements (29)
Predicate | Object |
---|---|
gptkbp:instanceOf |
biological pathway
|
gptkbp:activatedBy |
gptkb:STAT1
gptkb:STAT2 gptkb:IRF9 interferon-stimulated genes |
gptkbp:cause |
antiviral response
|
gptkbp:dysregulationAssociatedWith |
gptkb:cancer
autoimmune diseases viral infections |
gptkbp:foundIn |
humans
mammals vertebrates |
https://www.w3.org/2000/01/rdf-schema#label |
Interferon signaling pathway
|
gptkbp:involves |
gptkb:type_I_interferons
gptkb:JAK1 gptkb:STAT_proteins gptkb:TYK2 gptkb:interferon_receptors gptkb:JAK-STAT_pathway gptkb:type_III_interferons phosphorylation gene transcription interferons nuclear translocation ISGF3 complex type II interferons |
gptkbp:regulates |
immune response
|
gptkbp:bfsParent |
gptkb:STAT1
|
gptkbp:bfsLayer |
7
|