Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:cytokine
gptkb:insulin |
| gptkbp:alsoKnownAs |
interferon lambda
|
| gptkbp:binds |
IFNLR1 receptor
IL10R2 receptor |
| gptkbp:discoveredIn |
2003
|
| gptkbp:distinctFrom |
gptkb:type_I_interferons
type II interferons |
| gptkbp:function |
immune regulation
antiviral response |
| gptkbp:importantFor |
gastrointestinal tract immunity
respiratory tract immunity |
| gptkbp:includes |
IFN-λ1
IFN-λ2 IFN-λ3 IFN-λ4 |
| gptkbp:inducedBy |
interferon-stimulated genes
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_19_(human)
|
| gptkbp:mainlyActiveAt |
mucosal surfaces
|
| gptkbp:medicalUse |
hepatitis treatment (investigational)
|
| gptkbp:producedBy |
dendritic cells
epithelial cells |
| gptkbp:receptorExpression |
restricted to epithelial cells
|
| gptkbp:regulates |
adaptive immune response
innate immune response |
| gptkbp:bfsParent |
gptkb:Il-28R
gptkb:Interferon_signaling_pathway |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
type III interferons
|