type III interferons

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:insulin
cytokine
gptkbp:alsoKnownAs interferon lambda
gptkbp:binds IFNLR1 receptor
IL10R2 receptor
gptkbp:discoveredIn 2003
gptkbp:distinctFrom gptkb:type_I_interferons
type II interferons
gptkbp:function immune regulation
antiviral response
https://www.w3.org/2000/01/rdf-schema#label type III interferons
gptkbp:importantFor gastrointestinal tract immunity
respiratory tract immunity
gptkbp:includes IFN-λ1
IFN-λ2
IFN-λ3
IFN-λ4
gptkbp:inducedBy interferon-stimulated genes
gptkbp:locatedOnChromosome gptkb:chromosome_19_(human)
gptkbp:mainlyActiveAt mucosal surfaces
gptkbp:medicalUse hepatitis treatment (investigational)
gptkbp:producedBy dendritic cells
epithelial cells
gptkbp:receptorExpression restricted to epithelial cells
gptkbp:regulates adaptive immune response
innate immune response
gptkbp:bfsParent gptkb:Il-28R
gptkbp:bfsLayer 7