Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:insulin
cytokine |
gptkbp:alsoKnownAs |
interferon lambda
|
gptkbp:binds |
IFNLR1 receptor
IL10R2 receptor |
gptkbp:discoveredIn |
2003
|
gptkbp:distinctFrom |
gptkb:type_I_interferons
type II interferons |
gptkbp:function |
immune regulation
antiviral response |
https://www.w3.org/2000/01/rdf-schema#label |
type III interferons
|
gptkbp:importantFor |
gastrointestinal tract immunity
respiratory tract immunity |
gptkbp:includes |
IFN-λ1
IFN-λ2 IFN-λ3 IFN-λ4 |
gptkbp:inducedBy |
interferon-stimulated genes
|
gptkbp:locatedOnChromosome |
gptkb:chromosome_19_(human)
|
gptkbp:mainlyActiveAt |
mucosal surfaces
|
gptkbp:medicalUse |
hepatitis treatment (investigational)
|
gptkbp:producedBy |
dendritic cells
epithelial cells |
gptkbp:receptorExpression |
restricted to epithelial cells
|
gptkbp:regulates |
adaptive immune response
innate immune response |
gptkbp:bfsParent |
gptkb:Il-28R
|
gptkbp:bfsLayer |
7
|