|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CD18
integrin subunit beta 2
leukocyte adhesion deficiency antigen
|
|
gptkbp:associatedWith
|
Leukocyte adhesion deficiency
|
|
gptkbp:biologicalProcess
|
inflammatory response
protein binding
immune system process
cell-cell adhesion
integrin binding
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
integrin complex
|
|
gptkbp:component
|
gptkb:LFA-1
gptkb:Mac-1
alphaXbeta2 integrin
p150,95
|
|
gptkbp:encodes
|
integrin beta-2
|
|
gptkbp:Entrez_Gene_ID
|
3689
ENSG00000160255
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
monocytes
lymphocytes
neutrophils
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
immune response
cell adhesion
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasParalog
|
gptkb:ITGB1
ITGB3
ITGB4
ITGB5
ITGB6
ITGB7
ITGB8
|
|
gptkbp:HGNC_ID
|
6157
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ITGB2
|
|
gptkbp:interactsWith
|
gptkb:ICAM1
gptkb:ITGAL
gptkb:ITGAM
gptkb:ICAM3
ICAM2
ITGAX
|
|
gptkbp:locatedOnChromosome
|
21q22.3
|
|
gptkbp:mutationAssociatedWith
|
Leukocyte adhesion deficiency type 1
|
|
gptkbp:numberOfExons
|
16
|
|
gptkbp:OMIM
|
600065
|
|
gptkbp:orthologInMouse
|
Itgb2
|
|
gptkbp:product
|
gptkb:CD18
|
|
gptkbp:UniProtID
|
P05107
|
|
gptkbp:bfsParent
|
gptkb:CR3
gptkb:integrin_beta_2_(CD18)
|
|
gptkbp:bfsLayer
|
7
|