|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
G1P2
IFG15
UCRP
|
|
gptkbp:amendedBy
|
target proteins by ISGylation
|
|
gptkbp:associatedWith
|
immune response
congenital ISG15 deficiency
|
|
gptkbp:discoveredIn
|
1984
|
|
gptkbp:encodes
|
ISG15 protein
|
|
gptkbp:Entrez_Gene_ID
|
9636
ENSG00000187608
|
|
gptkbp:expressedIn
|
gptkb:breast
gptkb:cervix
gptkb:fallopian_tube
gptkb:gallbladder
gptkb:leukocytes
gptkb:thyroid
gptkb:cancer
gptkb:natural_killer_cells
gptkb:bone
gptkb:skin
gptkb:pituitary_gland
gptkb:skeletal_muscle
gptkb:B_cells
gptkb:T_cells
gptkb:adrenal_gland
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:small_intestine
gptkb:spinal_cord
gptkb:testis
gptkb:thymus
gptkb:urinary_bladder
blood
brain
eye
heart
retina
vagina
liver
collagen
spleen
tonsil
adipose tissue
bone marrow
colon
esophagus
lymph node
pancreas
parathyroid gland
salivary gland
stomach
peripheral neuropathy
tongue
dendritic cells
macrophages
appendix
endothelial cells
fibroblasts
smooth muscle
monocytes
ear
epithelial cells
nasal mucosa
granulocytes
fetal tissues
oral mucosa
lymphatic tissue
|
|
gptkbp:fullName
|
Interferon-stimulated gene 15
|
|
gptkbp:function
|
antiviral response
ubiquitin-like modifier
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ISG15
|
|
gptkbp:inducedBy
|
gptkb:type_I_interferons
gptkb:virus
type II interferons
|
|
gptkbp:involvedIn
|
histone modification
innate immune response
antiviral defense
|
|
gptkbp:length
|
165 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 1
|
|
gptkbp:molecularWeight
|
17 kDa
|
|
gptkbp:OMIM
|
147571
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Bos_taurus
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
1Z2M
3PHX
|
|
gptkbp:postTranslationalModification
|
ISGylation
|
|
gptkbp:regulates
|
protein function
protein stability
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:symbol
|
gptkb:ISG15
|
|
gptkbp:UniProtID
|
P05161
|
|
gptkbp:bfsParent
|
gptkb:Interferon-stimulated_gene
|
|
gptkbp:bfsLayer
|
7
|