Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
gptkb:IDO1
|
| gptkbp:associatedWith |
immune response
cancer immunosuppression |
| gptkbp:encodes |
gptkb:Indoleamine_2,3-dioxygenase_1
|
| gptkbp:Entrez_Gene_ID |
3620
ENSG00000131203 |
| gptkbp:enzymeCommissionNumber |
1.13.11.52
|
| gptkbp:expressedIn |
gptkb:cancer
gptkb:placenta dendritic cells macrophages |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
catalyzes the first step in tryptophan catabolism via the kynurenine pathway
|
| gptkbp:HGNC_ID |
HGNC:6059
|
| https://www.w3.org/2000/01/rdf-schema#label |
INDO1
|
| gptkbp:inhibitedBy |
1-methyl-tryptophan
|
| gptkbp:locatedOnChromosome |
8p22
|
| gptkbp:OMIM |
147780
|
| gptkbp:orthologIn |
Mus musculus (mouse): Ido1
Rattus norvegicus (rat): Ido1 |
| gptkbp:pathway |
gptkb:Kynurenine_pathway
gptkb:Tryptophan_metabolism |
| gptkbp:UniProtID |
P14902
|
| gptkbp:bfsParent |
gptkb:IDO1_gene
|
| gptkbp:bfsLayer |
8
|