Indoleamine 2,3-dioxygenase 1
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:abbreviation |
gptkb:IDO1
|
| gptkbp:associatedWith |
chronic inflammation
cancer immune escape |
| gptkbp:catalyzes |
oxidation of tryptophan to N-formylkynurenine
|
| gptkbp:cofactor |
hemoglobin
|
| gptkbp:EC_number |
1.13.11.52
|
| gptkbp:expressedIn |
gptkb:placenta
dendritic cells macrophages |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:gene |
gptkb:IDO1
|
| https://www.w3.org/2000/01/rdf-schema#label |
Indoleamine 2,3-dioxygenase 1
|
| gptkbp:inducedBy |
gptkb:interferon-gamma
|
| gptkbp:inhibitedBy |
1-methyl-tryptophan
|
| gptkbp:involves |
immune regulation
tryptophan catabolism |
| gptkbp:locatedOnChromosome |
gptkb:8p11.21
|
| gptkbp:structure |
monomeric protein
|
| gptkbp:target |
immunotherapy
|
| gptkbp:UniProtID |
P14902
|
| gptkbp:bfsParent |
gptkb:IDO1
|
| gptkbp:bfsLayer |
7
|