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gptkbp:instanceOf
|
biological pathway
|
|
gptkbp:dysregulationAssociatedWith
|
gptkb:cancer
gptkb:depression
schizophrenia
neurodegenerative diseases
autoimmune diseases
|
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gptkbp:enzyme
|
gptkb:kynureninase
gptkb:indoleamine_2,3-dioxygenase
gptkb:tryptophan_2,3-dioxygenase
gptkb:kynurenine_3-monooxygenase
gptkb:kynurenine_aminotransferase
aromatic L-amino acid decarboxylase
tryptophan hydroxylase
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Tryptophan metabolism
|
|
gptkbp:involves
|
tryptophan
|
|
gptkbp:location
|
brain
liver
|
|
gptkbp:occurredIn
|
animals
humans
plants
|
|
gptkbp:predecessor
|
gptkb:indole-3-acetic_acid
gptkb:picolinic_acid
gptkb:5-hydroxytryptophan
gptkb:5-hydroxyindoleacetic_acid
gptkb:formylkynurenine
gptkb:indole-3-aldehyde
gptkb:indole-3-lactic_acid
gptkb:indole-3-propionic_acid
gptkb:indoxyl_sulfate
gptkb:melatonin_sulfate
gptkb:nicotinamide_adenine_dinucleotide_(NAD+)
gptkb:quinolinic_acid
gptkb:serotonin_sulfate
gptkb:skatole
gptkb:tryptophol
gptkb:xanthurenic_acid
tryptamine
nicotinamide
3-hydroxyanthranilic acid
anthranilic acid
|
|
gptkbp:produces
|
gptkb:indole
gptkb:melatonin
gptkb:kynurenine
niacin
serotonin
|
|
gptkbp:regulates
|
cytokines
inflammation
cortisol
|
|
gptkbp:relatedTo
|
kynurenine pathway
serotonin biosynthesis
indole pathway
melatonin biosynthesis
niacin biosynthesis
|
|
gptkbp:bfsParent
|
gptkb:IDO1
|
|
gptkbp:bfsLayer
|
7
|