|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:CD182
gptkb:CXCR2
|
|
gptkbp:associatedWith
|
inflammatory diseases
chronic obstructive pulmonary disease
immune response
cystic fibrosis
inflammatory response
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:encodes
|
gptkb:C-X-C_chemokine_receptor_type_2
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000180871
3579
|
|
gptkbp:expressedIn
|
endothelial cells
monocytes
neutrophils
|
|
gptkbp:fullName
|
interleukin 8 receptor, beta
|
|
gptkbp:function
|
G-protein coupled receptor activity
chemokine receptor activity
|
|
gptkbp:geneLocationEnd
|
218,227,870
|
|
gptkbp:geneLocationStart
|
218,222,870
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasParalog
|
IL8RA
|
|
gptkbp:HGNC_ID
|
6026
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IL8RB
|
|
gptkbp:length
|
360
|
|
gptkbp:ligand
|
gptkb:interleukin-8
gptkb:CXCL1
gptkb:CXCL2
gptkb:CXCL3
gptkb:CXCL5
gptkb:CXCL6
gptkb:CXCL7
gptkb:CXCL8
|
|
gptkbp:locatedOnChromosome
|
2q35
|
|
gptkbp:molecularWeight
|
41 kDa
|
|
gptkbp:OMIM
|
146928
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Cxcr2
|
|
gptkbp:PDB
|
gptkb:5T1A
gptkb:6LFL
|
|
gptkbp:proteinFamily
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:regulates
|
angiogenesis
cell migration
neutrophil chemotaxis
|
|
gptkbp:strand
|
plus
|
|
gptkbp:transmembraneDomains
|
7
|
|
gptkbp:type
|
G-protein coupled pathway
|
|
gptkbp:UniProtID
|
gptkb:P25025
|
|
gptkbp:bfsParent
|
gptkb:CXCR2
|
|
gptkbp:bfsLayer
|
8
|