|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:CINC-2
GRO-gamma
GRO3
MIP-2-beta
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodedBy
|
CXCL3 gene
|
|
gptkbp:Entrez_Gene_ID
|
2921
ENSG00000163735
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
endothelial cells
fibroblasts
|
|
gptkbp:family
|
CXC chemokine family
|
|
gptkbp:fullName
|
C-X-C motif chemokine ligand 3
|
|
gptkbp:function
|
inflammatory response
chemotaxis
|
|
gptkbp:HGNC_ID
|
4605
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CXCL3
|
|
gptkbp:inducedBy
|
gptkb:IL-1
gptkb:TNF-alpha
|
|
gptkbp:involvedIn
|
wound healing
immune response
cancer metastasis
|
|
gptkbp:length
|
107 amino acids
|
|
gptkbp:locatedOnChromosome
|
4
4q21
|
|
gptkbp:molecularWeight
|
11 kDa
|
|
gptkbp:OMIM
|
182284
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
1MGS
|
|
gptkbp:postTranslationalModification
|
N-terminal processing
|
|
gptkbp:recipient
|
gptkb:CXCR2
|
|
gptkbp:regulates
|
upregulated by pro-inflammatory cytokines
|
|
gptkbp:relatedTo
|
gptkb:CXCL1
gptkb:CXCL2
gptkb:CXCL5
|
|
gptkbp:role
|
angiogenesis
tumor progression
neutrophil recruitment
|
|
gptkbp:secretes
|
macrophages
monocytes
epithelial cells
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
contains ELR motif
|
|
gptkbp:UniProtID
|
P19876
|
|
gptkbp:bfsParent
|
gptkb:CINC-2
gptkb:CXCR2
gptkb:CXC_domain
|
|
gptkbp:bfsLayer
|
8
|