Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alsoKnownAs |
epithelial-derived neutrophil-activating peptide 78
ENA-78 |
| gptkbp:category |
signaling molecule
cytokine |
| gptkbp:component |
extracellular region
|
| gptkbp:discoveredBy |
Harada et al.
|
| gptkbp:discoveredIn |
1993
|
| gptkbp:encodedBy |
CXCL5 gene
|
| gptkbp:Entrez_Gene_ID |
6374
ENSG00000163735 |
| gptkbp:fullName |
C-X-C motif chemokine ligand 5
|
| gptkbp:function |
angiogenesis
chemokine activity inflammatory response chemotaxis of neutrophils |
| gptkbp:gene |
gptkb:CXCL5
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:GOProcess |
neutrophil chemotaxis
|
| gptkbp:HGNC_ID |
10642
|
| https://www.w3.org/2000/01/rdf-schema#label |
CXCL5
|
| gptkbp:involvedIn |
wound healing
immune response tumor progression |
| gptkbp:length |
114
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_4q13-q21
4q13-q21 |
| gptkbp:molecularWeight |
12 kDa
|
| gptkbp:OMIM |
600324
|
| gptkbp:orthologIn |
present in mammals
mouse Cxcl5 |
| gptkbp:recipient |
gptkb:CXCR2
|
| gptkbp:RefSeq |
NM_002994
|
| gptkbp:regulates |
induced by IL-1
induced by TNF-alpha induced by LPS |
| gptkbp:secretes |
macrophages
endothelial cells fibroblasts monocytes epithelial cells |
| gptkbp:significance |
associated with cancer metastasis
elevated in inflammatory diseases potential biomarker for disease activity |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:structure |
contains CXC chemokine motif
|
| gptkbp:UniProtID |
P42830
|
| gptkbp:bfsParent |
gptkb:CXCR2
gptkb:CXC_domain |
| gptkbp:bfsLayer |
8
|