Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:alias |
gptkb:IL-10
gptkb:TGIF CSIF |
gptkbp:associatedWith |
autoimmune diseases
psoriasis rheumatoid arthritis inflammatory bowel disease |
gptkbp:discoveredBy |
Fiorentino et al.
|
gptkbp:discoveredIn |
1989
|
gptkbp:encodes |
interleukin-10 protein
|
gptkbp:Entrez_Gene_ID |
3586
ENSG00000136634 |
gptkbp:expressedIn |
gptkb:B_cells
gptkb:T_cells macrophages monocytes |
gptkbp:fullName |
interleukin 10
|
gptkbp:function |
anti-inflammatory cytokine
|
gptkbp:HGNC_ID |
HGNC:5962
|
https://www.w3.org/2000/01/rdf-schema#label |
IL10
|
gptkbp:locatedOnChromosome |
1
1q32.1 |
gptkbp:OMIM |
124092
|
gptkbp:organism |
gptkb:Homo_sapiens
|
gptkbp:regulates |
gptkb:JAK-STAT_signaling_pathway
gptkb:NF-kappaB_pathway immune response |
gptkbp:suppressedBy |
expression of pro-inflammatory cytokines
|
gptkbp:UniProtID |
gptkb:P22301
|
gptkbp:bfsParent |
gptkb:IL-10
gptkb:interleukin-10 |
gptkbp:bfsLayer |
8
|