|
gptkbp:instanceOf
|
gptkb:protein
cell surface receptor
|
|
gptkbp:alternativeName
|
CD124
IL4RA
|
|
gptkbp:associatedWith
|
gptkb:atopic_dermatitis
asthma
immunodeficiency
allergic diseases
|
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gptkbp:binds
|
gptkb:interleukin-4
gptkb:interleukin-13
|
|
gptkbp:domain
|
immunoglobulin-like domain
fibronectin type III domain
|
|
gptkbp:encodedBy
|
gptkb:IL4R_gene
|
|
gptkbp:expressedIn
|
gptkb:B_cells
gptkb:T_cells
gptkb:basophils
gptkb:mast_cells
dendritic cells
macrophages
|
|
gptkbp:formsComplexWith
|
gptkb:IL-13_receptor_alpha_1
gptkb:common_gamma_chain
|
|
gptkbp:function
|
regulates immune response
mediates IL-4 signaling
mediates IL-13 signaling
|
|
gptkbp:HGNC_ID
|
HGNC:6014
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IL-4 receptor alpha
|
|
gptkbp:locatedOnChromosome
|
gptkb:16p12.1
|
|
gptkbp:molecularWeight
|
approximately 80 kDa
|
|
gptkbp:OMIM
|
147781
|
|
gptkbp:PDB
|
3BPN
3BPO
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:species
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:target
|
gptkb:dupilumab
|
|
gptkbp:UniProtID
|
gptkb:P24394
|
|
gptkbp:bfsParent
|
gptkb:IL4_gene
|
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gptkbp:bfsLayer
|
7
|