|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
CD122
|
|
gptkbp:associatedWith
|
autoimmune diseases
immunodeficiency
immune response
|
|
gptkbp:component
|
gptkb:interleukin-2_receptor
gptkb:interleukin-15_receptor
|
|
gptkbp:discoveredBy
|
1980s
|
|
gptkbp:encodedBy
|
IL2RB gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000100385
|
|
gptkbp:expressedIn
|
gptkb:NK_cells
gptkb:B_cells
gptkb:T_cells
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
signal transduction
cytokine receptor activity
|
|
gptkbp:gene
|
gptkb:IL2RB
|
|
gptkbp:HGNC_ID
|
6009
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IL-2 receptor beta chain
|
|
gptkbp:interactsWith
|
gptkb:IL-2_receptor_alpha_chain
IL-2 receptor gamma chain
Janus kinase 1 (JAK1)
Janus kinase 3 (JAK3)
|
|
gptkbp:locatedOnChromosome
|
gptkb:22q13.1
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
approximately 70 kDa
|
|
gptkbp:OMIM
|
146710
|
|
gptkbp:PDB
|
2ERJ
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:RefSeq
|
NM_000878
|
|
gptkbp:role_in_therapy
|
target for immunotherapy
target for monoclonal antibodies
|
|
gptkbp:UniProtID
|
P14784
|
|
gptkbp:bfsParent
|
gptkb:CD25
|
|
gptkbp:bfsLayer
|
6
|