IL-2 receptor alpha chain

URI: https://gptkb.org/entity/IL-2_receptor_alpha_chain
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:CD25
gptkbp:component gptkb:interleukin-2_receptor
gptkbp:encodedBy gptkb:IL2RA_gene
gptkbp:expressedIn gptkb:B_cells
gptkb:regulatory_T_cells
dendritic cells
activated T cells
gptkbp:formsComplexWith gptkb:IL-2_receptor_beta_chain
IL-2 receptor gamma chain
gptkbp:function binds interleukin-2
regulates T cell proliferation
gptkbp:gene IL2RA
gptkbp:HGNC_ID 6008
https://www.w3.org/2000/01/rdf-schema#label IL-2 receptor alpha chain
gptkbp:locatedOnChromosome 10p15.1
gptkbp:location gptkb:cell_membrane
gptkbp:marking gptkb:regulatory_T_cells
gptkbp:molecularWeight approximately 55 kDa
gptkbp:mutationAssociatedWith multiple sclerosis
type 1 diabetes
autoimmune thyroid disease
gptkbp:OMIM 147730
gptkbp:role immune response
gptkbp:significance autoimmune diseases
immunodeficiency
gptkbp:structure single-pass type I membrane protein
gptkbp:target gptkb:basiliximab
gptkb:daclizumab
gptkbp:UniProtID P01589
gptkbp:bfsParent gptkb:CD25
gptkbp:bfsLayer 6