Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:IL-2_receptor_alpha_chain
|
| gptkbp:associatedWith |
leukemia
autoimmune diseases |
| gptkbp:component |
gptkb:interleukin-2_receptor
|
| gptkbp:encodedBy |
gptkb:IL2RA_gene
|
| gptkbp:Entrez_Gene_ID |
3559
|
| gptkbp:expressedIn |
gptkb:regulatory_T_cells
gptkb:thymus lymph nodes spleen dendritic cells activated T cells activated B cells |
| gptkbp:formsComplexWith |
gptkb:common_gamma_chain
gptkb:IL-2_receptor_beta_chain |
| gptkbp:function |
modulates immune response
binds interleukin-2 |
| gptkbp:HGNC_ID |
6008
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD25
|
| gptkbp:locatedOnChromosome |
10p15
|
| gptkbp:molecularWeight |
55 kDa
|
| gptkbp:OMIM |
147730
|
| gptkbp:requires |
high-affinity IL-2 binding
|
| gptkbp:structure |
single-pass type I membrane protein
|
| gptkbp:target |
gptkb:basiliximab
gptkb:daclizumab |
| gptkbp:UniProtID |
P01589
|
| gptkbp:usedAs |
marker for regulatory T cells
|
| gptkbp:bfsParent |
gptkb:Simulect
|
| gptkbp:bfsLayer |
5
|