|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CD25
p55
Tac antigen
|
|
gptkbp:associatedWith
|
multiple sclerosis
type 1 diabetes
autoimmune diseases
|
|
gptkbp:discoveredBy
|
Takeshita et al.
|
|
gptkbp:encodes
|
Interleukin-2 receptor alpha chain
|
|
gptkbp:Entrez_Gene_ID
|
3559
ENSG00000134460
|
|
gptkbp:expressedIn
|
gptkb:T_cells
gptkb:regulatory_T_cells
|
|
gptkbp:firstDescribed
|
1985
|
|
gptkbp:function
|
forms part of the high-affinity IL-2 receptor
|
|
gptkbp:HGNC_ID
|
HGNC:6008
|
|
gptkbp:length
|
272 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_10
10p15.1
|
|
gptkbp:mutationAssociatedWith
|
gptkb:immunodeficiency
autoimmunity
|
|
gptkbp:OMIM
|
147730
|
|
gptkbp:orthologInMouse
|
Il2ra
|
|
gptkbp:product
|
type I membrane protein
CD25 protein
|
|
gptkbp:regulates
|
gptkb:immune_response
T cell proliferation
|
|
gptkbp:targetOfDrug
|
gptkb:basiliximab
gptkb:daclizumab
|
|
gptkbp:UniProtID
|
P01589
|
|
gptkbp:bfsParent
|
gptkb:interleukin-2_receptor
gptkb:P28908
gptkb:CD25
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IL2RA gene
|