Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
gptkb:CD25
p55 Tac antigen |
| gptkbp:associatedWith |
multiple sclerosis
type 1 diabetes autoimmune diseases |
| gptkbp:discoveredBy |
Takeshita et al.
|
| gptkbp:encodes |
Interleukin-2 receptor alpha chain
|
| gptkbp:Entrez_Gene_ID |
3559
ENSG00000134460 |
| gptkbp:expressedIn |
gptkb:T_cells
gptkb:regulatory_T_cells |
| gptkbp:firstDescribed |
1985
|
| gptkbp:function |
forms part of the high-affinity IL-2 receptor
|
| gptkbp:HGNC_ID |
HGNC:6008
|
| https://www.w3.org/2000/01/rdf-schema#label |
IL2RA gene
|
| gptkbp:length |
272 amino acids
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_10
10p15.1 |
| gptkbp:mutationAssociatedWith |
immunodeficiency
autoimmunity |
| gptkbp:OMIM |
147730
|
| gptkbp:orthologInMouse |
Il2ra
|
| gptkbp:product |
type I membrane protein
CD25 protein |
| gptkbp:regulates |
immune response
T cell proliferation |
| gptkbp:targetOfDrug |
gptkb:basiliximab
gptkb:daclizumab |
| gptkbp:UniProtID |
P01589
|
| gptkbp:bfsParent |
gptkb:CD25
|
| gptkbp:bfsLayer |
6
|