Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:receptor_tyrosine_kinase
gptkb:protein |
| gptkbp:alternativeName |
gptkb:Cation-independent_mannose-6-phosphate_receptor
gptkb:Insulin-like_growth_factor_2_receptor |
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:binds |
gptkb:IGF-2
mannose-6-phosphate-containing proteins |
| gptkbp:domain |
extracellular domain
transmembrane domain cytoplasmic tail |
| gptkbp:encodedBy |
gptkb:IGF2R_gene
|
| gptkbp:Entrez_Gene_ID |
3482
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
lysosomal enzyme trafficking
regulation of IGF-2 availability |
| https://www.w3.org/2000/01/rdf-schema#label |
IGF-2 receptor
|
| gptkbp:locatedOnChromosome |
chromosome 6q25.3
|
| gptkbp:location |
gptkb:cell_membrane
gptkb:Golgi_apparatus |
| gptkbp:molecularWeight |
~300 kDa
|
| gptkbp:OMIM |
147280
|
| gptkbp:UniProtID |
P11717
|
| gptkbp:bfsParent |
gptkb:IGF-II
gptkb:somatomedin-A gptkb:insulin-like_growth_factors |
| gptkbp:bfsLayer |
7
|