Insulin-like growth factor 2 receptor
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:associatedWith |
gptkb:cancer
growth regulation |
| gptkbp:discoveredBy |
Willy J. M. van den Berg
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:IGF2R_gene
|
| gptkbp:Entrez_Gene_ID |
3482
|
| gptkbp:expressedIn |
many human tissues
|
| gptkbp:function |
lysosomal enzyme trafficking
binds insulin-like growth factor 2 regulates IGF2 availability |
| gptkbp:HGNC_ID |
HGNC:5446
|
| https://www.w3.org/2000/01/rdf-schema#label |
Insulin-like growth factor 2 receptor
|
| gptkbp:locatedIn |
gptkb:human_chromosome_6
|
| gptkbp:location |
gptkb:cell_membrane
gptkb:Golgi_apparatus endosomes lysosomes |
| gptkbp:molecularWeight |
~300 kDa
|
| gptkbp:OMIM |
147280
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:otherName |
cation-independent mannose-6-phosphate receptor
|
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:symbol |
gptkb:IGF2R
|
| gptkbp:UniProtID |
P11717
|
| gptkbp:bfsParent |
gptkb:IGF2_receptor
|
| gptkbp:bfsLayer |
7
|