Cation-independent mannose-6-phosphate receptor
GPTKB entity
Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alsoKnownAs |
gptkb:IGF2R
|
gptkbp:associatedWith |
gptkb:cancer
lysosomal storage disorders |
gptkbp:discoveredBy |
Stuart Kornfeld
|
gptkbp:encodedBy |
gptkb:IGF2R_gene
|
gptkbp:foundIn |
gptkb:Homo_sapiens
|
gptkbp:function |
insulin-like growth factor 2 binding
lysosomal enzyme trafficking |
gptkbp:GO |
GO:0005040
|
https://www.w3.org/2000/01/rdf-schema#label |
Cation-independent mannose-6-phosphate receptor
|
gptkbp:ligand |
gptkb:insulin-like_growth_factor_2
gptkb:mannose-6-phosphate |
gptkbp:locatedOnChromosome |
chromosome 6q25.3
|
gptkbp:location |
gptkb:trans-Golgi_network
gptkb:plasma_membrane endosomes |
gptkbp:molecularWeight |
~300 kDa
|
gptkbp:OMIM |
147280
|
gptkbp:orthologIn |
cation-dependent mannose-6-phosphate receptor
|
gptkbp:recipient |
transmembrane glycoprotein
|
gptkbp:species |
gptkb:human
gptkb:mouse right |
gptkbp:structure |
15 repeating domains
|
gptkbp:UniProtID |
P11717
|
gptkbp:bfsParent |
gptkb:IGF2_receptor
|
gptkbp:bfsLayer |
7
|