Human serotonin receptor 5-HT1B

URI: https://gptkb.org/entity/Human_serotonin_receptor_5-HT1B
GPTKB entity
Statements (37)
Predicate Object
gptkbp:instanceOf gptkb:receptor_tyrosine_kinase
gptkb:G_protein-coupled_receptor
gptkbp:alternativeName gptkb:5-HT1B_receptor
gptkb:5-hydroxytryptamine_receptor_1B
gptkbp:associatedWith gptkb:substance_abuse
gptkb:depression
anxiety
aggression
migraine
gptkbp:biologicalProcess G protein-coupled serotonin receptor activity
gptkbp:encodedBy gptkb:HTR1B_gene
gptkbp:Entrez_Gene_ID 3351
gptkbp:expressedIn brain
vascular smooth muscle
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:HGNC_ID 5292
gptkbp:involvedIn neurotransmission
regulation of mood
vasoconstriction
modulation of dopamine release
gptkbp:ligand serotonin
gptkbp:locatedOnChromosome chromosome 6q13
gptkbp:OMIM 182131
gptkbp:orthologIn gptkb:mouse
gptkb:right
gptkbp:PDB 4IAR
gptkbp:RefSeq NP_000854
gptkbp:targetOfDrug gptkb:triptans
antipsychotics
antidepressants
gptkbp:transmembraneDomains true
gptkbp:type inhibits adenylate cyclase via Gi/o protein
gptkbp:UniProtID P28222
gptkbp:bfsParent gptkb:P30989
gptkb:P48061
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label Human serotonin receptor 5-HT1B