5-hydroxytryptamine receptor 1B

URI: https://gptkb.org/entity/5-hydroxytryptamine_receptor_1B
GPTKB entity
Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:G_protein-coupled_receptor
gptkbp:alternativeName gptkb:5-HT1B_receptor
Serotonin receptor 1B
gptkbp:associatedWith gptkb:depression
anxiety
aggressive behavior
migraine
gptkbp:biologicalProcess G protein-coupled receptor signaling pathway
serotonin receptor activity
regulation of neurotransmitter levels
gptkbp:cellularComponent gptkb:plasma_membrane
gptkbp:encodedBy gptkb:HTR1B_gene
gptkbp:enemyOf gptkb:zolmitriptan
sumatriptan
GR 127935
SB-216641
CP-93129
SB-224289
isamoltane
gptkbp:Entrez_Gene_ID 3351
ENSG00000169710
gptkbp:expressedIn brain
vascular smooth muscle
gptkbp:family serotonin receptor family
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:hasRole vasoconstriction
modulation of neurotransmitter release
gptkbp:HGNC_ID 5292
https://www.w3.org/2000/01/rdf-schema#label 5-hydroxytryptamine receptor 1B
gptkbp:length 390
gptkbp:ligand serotonin
gptkbp:locatedOnChromosome 6q13
gptkbp:molecularWeight 43 kDa
gptkbp:OMIM 182131
gptkbp:orthologIn gptkb:Mus_musculus
gptkb:Rattus_norvegicus
gptkbp:PDB 4IAR
6G79
gptkbp:RefSeq NM_000863
gptkbp:subfamily 5-HT1 receptor subfamily
gptkbp:transmembraneDomains true
gptkbp:type inhibits adenylate cyclase
gptkbp:UniProtID P28222
gptkbp:bfsParent gptkb:5-HT1B_receptor
gptkb:P30989
gptkb:P48061
gptkb:HTR1B
gptkb:HTR1B_gene
gptkbp:bfsLayer 8