|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
5-HT1B
serotonin receptor 1B
5HT1B
|
|
gptkbp:associatedWith
|
neurotransmission
psychiatric disorders
serotonin signaling
|
|
gptkbp:discoveredBy
|
Lesch et al.
|
|
gptkbp:discoveredIn
|
1988
|
|
gptkbp:encodes
|
gptkb:5-hydroxytryptamine_receptor_1B
|
|
gptkbp:Entrez_Gene_ID
|
3351
ENSG00000169710
|
|
gptkbp:expressedIn
|
brain
central nervous system
|
|
gptkbp:function
|
regulation of mood
modulation of neurotransmitter release
regulation of behavior
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
5292
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HTR1B gene
|
|
gptkbp:length
|
1,728 base pairs (mRNA)
|
|
gptkbp:locatedOnChromosome
|
6q13
|
|
gptkbp:mutationAssociatedWith
|
gptkb:autism_spectrum_disorder
drug addiction
migraine
impulsivity
alcohol dependence
psychiatric phenotypes
|
|
gptkbp:numberOfExons
|
1
|
|
gptkbp:OMIM
|
182131
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Htr1b
|
|
gptkbp:pathway
|
gptkb:cAMP_signaling_pathway
neuroactive ligand-receptor interaction
serotonergic synapse
GPCR signaling
|
|
gptkbp:product
|
gptkb:5-HT1B_receptor
|
|
gptkbp:recipient
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:relatedTo
|
gptkb:depression
anxiety
substance abuse
aggression
|
|
gptkbp:targetOfDrug
|
gptkb:triptans
antagonists
antipsychotics
antidepressants
agonists
|
|
gptkbp:UniProtID
|
P28222
|
|
gptkbp:bfsParent
|
gptkb:5-HT1_receptor
|
|
gptkbp:bfsLayer
|
7
|