|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:approvedBy
|
1991
|
|
gptkbp:ATCCode
|
gptkb:N02CC
|
|
gptkbp:compatibleWith
|
migraine prevention
|
|
gptkbp:contraindication
|
gptkb:basilar_migraine
gptkb:hemiplegic_migraine
ischemic heart disease
uncontrolled hypertension
|
|
gptkbp:discoveredBy
|
gptkb:Glaxo_(sumatriptan)
|
|
gptkbp:drugClass
|
gptkb:rizatriptan
gptkb:almotriptan
gptkb:eletriptan
gptkb:frovatriptan
gptkb:naratriptan
gptkb:zolmitriptan
sumatriptan
|
|
gptkbp:eliminationHalfLife
|
varies by agent
|
|
gptkbp:example
|
gptkb:rizatriptan
gptkb:almotriptan
gptkb:eletriptan
gptkb:frovatriptan
gptkb:naratriptan
gptkb:zolmitriptan
sumatriptan
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
triptans
|
|
gptkbp:mechanismOfAction
|
serotonin receptor agonist
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:routeOfAdministration
|
oral
subcutaneous
nasal
|
|
gptkbp:sideEffect
|
dizziness
tingling
chest discomfort
|
|
gptkbp:target
|
gptkb:5-HT1B_receptor
gptkb:5-HT1D_receptor
|
|
gptkbp:usedFor
|
migraine treatment
|
|
gptkbp:bfsParent
|
gptkb:receptor_tyrosine_kinase
gptkb:SSRIs
gptkb:ergotamine
|
|
gptkbp:bfsLayer
|
6
|