|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:HSC70
gptkb:Heat_shock_cognate_71_kDa_protein
|
|
gptkbp:biologicalProcess
|
autophagy
protein refolding
response to heat
|
|
gptkbp:encodedBy
|
gptkb:HSPA8_gene
|
|
gptkbp:Entrez_Gene_ID
|
3312
ENSG00000109971
|
|
gptkbp:expressedIn
|
all human tissues
|
|
gptkbp:function
|
protein folding
ATP binding
molecular chaperone
prevention of protein aggregation
unfolded protein binding
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HSPA8
|
|
gptkbp:interactsWith
|
gptkb:BAG1
gptkb:BAG3
gptkb:DNAJB1
STUB1
|
|
gptkbp:involvedIn
|
autophagy
cellular stress response
protein transport
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_11q24.1
|
|
gptkbp:location
|
gptkb:lysosome
gptkb:nucleus
gptkb:cytoplasm
cytosol
|
|
gptkbp:memberOf
|
gptkb:heat_shock_protein_70_family
|
|
gptkbp:molecularWeight
|
71 kDa
|
|
gptkbp:OMIM
|
600816
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
gptkb:4PO2
gptkb:3ATX
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:RefSeq
|
NM_006597
|
|
gptkbp:regulates
|
constitutively expressed
upregulated by stress
|
|
gptkbp:requires
|
cell viability
|
|
gptkbp:structure
|
ATPase domain
substrate-binding domain
|
|
gptkbp:UniProtID
|
P11142
|
|
gptkbp:bfsParent
|
gptkb:HSP70
gptkb:heat_shock_protein_70_family
|
|
gptkbp:bfsLayer
|
7
|