|
gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
|
BCL2-associated athanogene family protein 3
BCL2-associated athanogene-3
CAIR-1
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:dilated_cardiomyopathy
myofibrillar myopathy
|
|
gptkbp:domain
|
gptkb:WW_domain
BAG domain
IPV motif
PXXP motif
|
|
gptkbp:encodedBy
|
BAG3 gene
|
|
gptkbp:Entrez_Gene_ID
|
9531
ENSG00000105852
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
heart
various cancers
|
|
gptkbp:fullName
|
BCL2-associated athanogene 3
|
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gptkbp:function
|
regulation of apoptosis
cytoskeleton organization
autophagy regulation
co-chaperone
|
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gptkbp:gene
|
gptkb:BAG3
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BAG3
|
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gptkbp:interactsWith
|
gptkb:14-3-3_proteins
gptkb:BCL2
gptkb:Hsp70
HspB8
|
|
gptkbp:length
|
575
|
|
gptkbp:locatedOnChromosome
|
10q26.11
|
|
gptkbp:molecularWeight
|
61 kDa
|
|
gptkbp:mutationAssociatedWith
|
muscle weakness
protein aggregation
cardiomyopathy
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:regulates
|
apoptosis
cell survival
protein quality control
autophagy
stress response
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
Z-disc of muscle fibers
|
|
gptkbp:UniProtID
|
O95817
|
|
gptkbp:bfsParent
|
gptkb:HSPB8
gptkb:HSPA8
gptkb:HSPB1
|
|
gptkbp:bfsLayer
|
8
|