|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CYP2D
gptkb:P450DB1
gptkb:CYP2D7
gptkb:CPD6
gptkb:CYP2D8P
|
|
gptkbp:approvedBy
|
gptkb:cytochrome_P450_family_2_subfamily_D_member_6
|
|
gptkbp:approvedSymbol
|
gptkb:CYP2D6
|
|
gptkbp:associatedWith
|
gptkb:codeine
gptkb:tamoxifen
gptkb:adverse_drug_reaction
beta blockers
opioids
antipsychotics
antidepressants
poor metabolizer phenotype
ultrarapid metabolizer phenotype
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000100197
1565
|
|
gptkbp:expressedIn
|
gptkb:kidney
gptkb:small_intestine
brain
liver
|
|
gptkbp:function
|
drug metabolism
xenobiotic metabolism
|
|
gptkbp:hasPseudogene
|
gptkb:CYP2D7
gptkb:CYP2D8P
|
|
gptkbp:hasVariant
|
CYP2D6*10
CYP2D6*17
CYP2D6*4
CYP2D6*41
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:2194
|
|
gptkbp:isPolymorphic
|
true
|
|
gptkbp:locatedOnChromosome
|
22
|
|
gptkbp:location
|
gptkb:22q13.2
|
|
gptkbp:locusType
|
gptkb:gene
gene with protein product
|
|
gptkbp:OMIM
|
124030
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Cyp2d22
gptkb:rat_Cyp2d1
|
|
gptkbp:partOf
|
gptkb:cytochrome_P450_superfamily
|
|
gptkbp:previousName
|
gptkb:debrisoquine_4-hydroxylase
gptkb:cytochrome_P450,_subfamily_IID,_polypeptide_1
|
|
gptkbp:previousSymbols
|
gptkb:CYP2D
gptkb:P450DB1
|
|
gptkbp:proteinFamily
|
gptkb:cytochrome_P450
gptkb:CYP2D_subfamily
|
|
gptkbp:RefSeq
|
gptkb:NM_000106
|
|
gptkbp:target
|
pharmacogenomics testing
|
|
gptkbp:UniProtID
|
P10635
|
|
gptkbp:bfsParent
|
gptkb:COL1A2
|
|
gptkbp:bfsLayer
|
8
|
|
http://www.w3.org/2000/01/rdf-schema#label
|
HGNC:2194
|