Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
antihistamine |
| gptkbp:activatedBy |
gptkb:inositol_phosphate_pathway
gptkb:phospholipase_C |
| gptkbp:alternativeName |
gptkb:Histamine_H1_receptor
gptkb:HRH1 |
| gptkbp:biologicalProcess |
G protein-coupled receptor activity
|
| gptkbp:discoveredIn |
1960s
|
| gptkbp:encodedBy |
gptkb:HRH1_gene
|
| gptkbp:expressedIn |
central nervous system
peripheral nervous system endothelial cells smooth muscle |
| gptkbp:foundIn |
gptkb:human
mammals |
| gptkbp:function |
involved in inflammation
mediates effects of histamine involved in neurotransmission involved in allergic response |
| https://www.w3.org/2000/01/rdf-schema#label |
H1 receptor
|
| gptkbp:locatedIn |
gptkb:cell_membrane
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_3p25
|
| gptkbp:target |
gptkb:H1_antagonists
antihistamines |
| gptkbp:UniProtID |
gptkb:P35367
|
| gptkbp:bfsParent |
gptkb:antihistamine
|
| gptkbp:bfsLayer |
6
|