|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:RSS
GRBIR
MEG7
hGrbIR
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
growth regulation
metabolic disorders
|
|
gptkbp:encodes
|
Growth factor receptor-bound protein 10
|
|
gptkbp:Entrez_Gene_ID
|
2887
ENSG00000106070
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
gptkb:placenta
brain
liver
pancreas
|
|
gptkbp:function
|
regulation of insulin signaling
adaptor protein
regulation of growth factor signaling
|
|
gptkbp:HGNC_ID
|
4567
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Grb10
|
|
gptkbp:imprint
|
maternally expressed in some tissues
paternally expressed in other tissues
|
|
gptkbp:interactsWith
|
gptkb:IGF1_receptor
gptkb:insulin_receptor
gptkb:Epidermal_growth_factor_receptor
|
|
gptkbp:locatedOnChromosome
|
chromosome 7p12.1
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Silver-Russell_syndrome
growth retardation
|
|
gptkbp:OMIM
|
601523
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Grb10
|
|
gptkbp:proteinFamily
|
gptkb:PH_domain
SH2 domain
BPS domain
|
|
gptkbp:regulates
|
apoptosis
cell proliferation
glucose metabolism
|
|
gptkbp:species
|
gptkb:human
gptkb:mouse
|
|
gptkbp:UniProtID
|
Q13322
|
|
gptkbp:bfsParent
|
gptkb:NEDD4-1
|
|
gptkbp:bfsLayer
|
6
|