|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:glutamic_acid_decarboxylase_2
gptkb:GAD65
|
|
gptkbp:associatedWith
|
epilepsy
schizophrenia
type 1 diabetes
|
|
gptkbp:biologicalProcess
|
gptkb:GABA_biosynthetic_process
pyridoxal phosphate binding
|
|
gptkbp:cellularComponent
|
gptkb:cytoplasm
synaptic vesicle membrane
|
|
gptkbp:encodes
|
gptkb:glutamate_decarboxylase_enzyme_(GAD65)
|
|
gptkbp:Entrez_Gene_ID
|
2572
|
|
gptkbp:enzymeCommissionNumber
|
4.1.1.15
|
|
gptkbp:expressedIn
|
gptkb:pancreatic_islets
central nervous system
|
|
gptkbp:fullName
|
gptkb:glutamate_decarboxylase_2
|
|
gptkbp:function
|
catalyzes conversion of glutamate to GABA
|
|
gptkbp:HGNC_ID
|
4092
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GAD2
|
|
gptkbp:locatedOnChromosome
|
chromosome 10q23.33
|
|
gptkbp:mutationAssociatedWith
|
may affect GABA levels
|
|
gptkbp:OMIM
|
600922
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
Mus musculus (mouse)
|
|
gptkbp:product
|
gptkb:GAD65
|
|
gptkbp:regulates
|
regulated by alternative splicing
|
|
gptkbp:relatedTo
|
GABAergic neurotransmission
autoimmune response in diabetes
neurotransmitter metabolism
|
|
gptkbp:UniProtID
|
gptkb:Q99259
|
|
gptkbp:bfsParent
|
gptkb:glutamic_acid_decarboxylase
|
|
gptkbp:bfsLayer
|
6
|