glutamate decarboxylase enzyme (GAD65)
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:glutamate_decarboxylase_2
gptkb:GAD65 |
| gptkbp:autoantigenIn |
gptkb:Stiff-person_syndrome
type 1 diabetes |
| gptkbp:catalyzes |
conversion of glutamate to GABA
|
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:EC_number |
4.1.1.15
|
| gptkbp:encodedBy |
gptkb:GAD2_gene
|
| gptkbp:expressedIn |
gptkb:pancreatic_islets
gptkb:neurons |
| gptkbp:foundIn |
central nervous system
pancreatic beta cells |
| gptkbp:function |
GABA biosynthesis
|
| gptkbp:hasIsoform |
gptkb:GAD67
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_10p11.23
|
| gptkbp:medicalUse |
autoantibody marker for type 1 diabetes
|
| gptkbp:molecularWeight |
65 kDa
|
| gptkbp:OMIM |
138275
|
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:structure |
homodimer
|
| gptkbp:subcellularLocation |
cytosol
synaptic terminals |
| gptkbp:UniProtID |
Q05329
|
| gptkbp:bfsParent |
gptkb:GAD2
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
glutamate decarboxylase enzyme (GAD65)
|