glutamic acid decarboxylase 2
GPTKB entity
Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:GAD65
|
| gptkbp:antigen_for |
autoantibodies in type 1 diabetes
|
| gptkbp:associatedWith |
type 1 diabetes
|
| gptkbp:biologicalProcess |
glutamate decarboxylase activity
|
| gptkbp:catalyzes |
decarboxylation of glutamate to GABA
|
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:EC_number |
4.1.1.15
|
| gptkbp:expressedIn |
gptkb:pancreatic_islets
brain |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:gene |
gptkb:GAD2
|
| https://www.w3.org/2000/01/rdf-schema#label |
glutamic acid decarboxylase 2
|
| gptkbp:involves |
GABAergic neurotransmission
|
| gptkbp:locatedIn |
gptkb:cytoplasm
|
| gptkbp:locatedOnChromosome |
chromosome 10q23.33
|
| gptkbp:OMIM |
138275
|
| gptkbp:proteinFamily |
pyridoxal-dependent decarboxylase family
|
| gptkbp:subunit |
homodimer
|
| gptkbp:UniProtID |
gptkb:Q99259
|
| gptkbp:bfsParent |
gptkb:GAD2
|
| gptkbp:bfsLayer |
7
|