Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:Glutamic_acid_decarboxylase_2
gptkb:GAD2 |
| gptkbp:autoantigenIn |
type 1 diabetes
|
| gptkbp:EC_number |
4.1.1.15
|
| gptkbp:encodedBy |
gptkb:GAD2_gene
|
| gptkbp:expressedIn |
central nervous system
pancreatic beta cells |
| gptkbp:fullName |
gptkb:Glutamate_decarboxylase_65
|
| gptkbp:function |
catalyzes conversion of glutamate to GABA
|
| https://www.w3.org/2000/01/rdf-schema#label |
GAD65
|
| gptkbp:inhibitedBy |
antibodies in type 1 diabetes
|
| gptkbp:locatedOnChromosome |
chromosome 10q23.33
|
| gptkbp:location |
gptkb:cytoplasm
synaptic vesicles |
| gptkbp:molecularWeight |
65 kDa
|
| gptkbp:structure |
pyridoxal phosphate-dependent enzyme
|
| gptkbp:usedIn |
diagnosis of autoimmune diabetes
|
| gptkbp:bfsParent |
gptkb:glutamic_acid_decarboxylase
|
| gptkbp:bfsLayer |
6
|