Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:glutamic_acid_decarboxylase_2
gptkb:GAD65 GAD-2 |
| gptkbp:associatedWith |
type 1 diabetes
stiff-person syndrome autoimmune encephalitis |
| gptkbp:biologicalProcess |
gptkb:GABA_biosynthetic_process
pyridoxal phosphate binding |
| gptkbp:catalyzes |
conversion of glutamate to GABA
|
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:EC_number |
4.1.1.15
|
| gptkbp:encodes |
GAD65 protein
|
| gptkbp:Entrez_Gene_ID |
ENSG00000128683
|
| gptkbp:expressedIn |
brain
pancreas |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:gene |
gptkb:GAD2
|
| gptkbp:HGNC_ID |
4093
|
| https://www.w3.org/2000/01/rdf-schema#label |
glutamate decarboxylase 2
|
| gptkbp:length |
585 amino acids
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_10
10p12.1 |
| gptkbp:OMIM |
605363
|
| gptkbp:orthologInMouse |
gptkb:Gad2
|
| gptkbp:RefSeq |
NM_000825
|
| gptkbp:subcellularLocation |
gptkb:cytoplasm
synaptic vesicle membrane |
| gptkbp:UniProtID |
gptkb:Q99259
|
| gptkbp:bfsParent |
gptkb:GAD2
|
| gptkbp:bfsLayer |
7
|