Statements (20)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:affectsPrognosis |
poor prognosis in rhabdomyosarcoma
|
gptkbp:altersGeneExpression |
myogenic regulatory genes
|
gptkbp:associatedWith |
gptkb:alveolar_rhabdomyosarcoma
|
gptkbp:chromosomalTranslocation |
t(2;13)(q35;q14)
|
gptkbp:compatibleWith |
normal tissue
|
gptkbp:discoveredIn |
1993
|
gptkbp:encodes |
chimeric transcription factor
|
gptkbp:expressedIn |
tumor cells
|
https://www.w3.org/2000/01/rdf-schema#label |
PAX3-FOXO1
|
gptkbp:mergedInto |
gptkb:FOXO1
gptkb:PAX3 |
gptkbp:regulates |
apoptosis
cell differentiation cell proliferation |
gptkbp:studiedIn |
cancer research
|
gptkbp:target |
molecular therapies
|
gptkbp:usedAsDiagnosticMarker |
gptkb:alveolar_rhabdomyosarcoma
|
gptkbp:bfsParent |
gptkb:FOXO1
|
gptkbp:bfsLayer |
7
|