|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:FOXO1
gptkb:FKHR
|
|
gptkbp:associatedWith
|
gptkb:diabetes_mellitus
gptkb:rhabdomyosarcoma
|
|
gptkbp:encodes
|
gptkb:Forkhead_box_protein_O1
|
|
gptkbp:Entrez_Gene_ID
|
2308
ENSG00000150907
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
liver
adipose tissue
|
|
gptkbp:fusionGeneWith
|
gptkb:PAX3
gptkb:PAX7
|
|
gptkbp:HGNC_ID
|
HGNC:3819
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FOXO1A
|
|
gptkbp:involvedIn
|
gptkb:PI3K-AKT_signaling_pathway
insulin signaling pathway
cellular response to oxidative stress
gluconeogenesis
|
|
gptkbp:locatedOnChromosome
|
13q14.11
|
|
gptkbp:memberOf
|
gptkb:FOXO_subfamily
|
|
gptkbp:modulatedBy
|
gptkb:insulin
gptkb:AKT_kinase
|
|
gptkbp:mutationAssociatedWith
|
Alveolar rhabdomyosarcoma
|
|
gptkbp:orthologInMouse
|
gptkb:Foxo1
|
|
gptkbp:phosphorylates
|
Ser256
Ser319
Thr24
|
|
gptkbp:proteinFamily
|
forkhead box domain
|
|
gptkbp:regulates
|
apoptosis
yes
glucose metabolism
cell cycle
oxidative stress response
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:UniProtID
|
Q12778
|
|
gptkbp:bfsParent
|
gptkb:FOXO1
|
|
gptkbp:bfsLayer
|
7
|