|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:FOXO1
gptkb:FOXO1A
Forkhead in Rhabdomyosarcoma
|
|
gptkbp:encodes
|
gptkb:Forkhead_box_protein_O1
|
|
gptkbp:Entrez_Gene_ID
|
2308
ENSG00000150907
|
|
gptkbp:expressedIn
|
gptkb:adipose_tissue
gptkb:skeletal_muscle
liver
|
|
gptkbp:formsFusionGeneWith
|
gptkb:PAX3
gptkb:PAX3-FOXO1
gptkb:PAX7
gptkb:PAX7-FOXO1
|
|
gptkbp:function
|
gptkb:transcription_factor
|
|
gptkbp:HGNC_ID
|
HGNC:3819
|
|
gptkbp:locatedOnChromosome
|
13q14.11
|
|
gptkbp:memberOf
|
gptkb:FOXO_subfamily
|
|
gptkbp:mutationAssociatedWith
|
gptkb:alveolar_rhabdomyosarcoma
gptkb:rhabdomyosarcoma
|
|
gptkbp:OMIM
|
136533
|
|
gptkbp:PDB
|
3COA
2UZK
|
|
gptkbp:phosphorylates
|
gptkb:AKT1
gptkb:SGK
|
|
gptkbp:regulates
|
gptkb:immune_response
apoptosis
DNA repair
lipid metabolism
cellular senescence
angiogenesis
muscle atrophy
glucose metabolism
oxidative phosphorylation
cell cycle
stem cell maintenance
autophagy
tumor suppression
oxidative stress response
insulin signaling
mitochondrial biogenesis
adipogenesis
cellular differentiation
gluconeogenesis
oxidative stress resistance
|
|
gptkbp:UniProtID
|
Q12778
|
|
gptkbp:bfsParent
|
gptkb:FOXO
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FKHR (FOXO1)
|